SNPs are
the most common form of DNA sequence variation. They are useful
polymorphic markers to investigate genes susceptible to diseases
or those related to drug responsiveness. Furthermore, a small subset
of SNPs directly influences to the quality and/or quantity of the
gene product, and increase a risk to certain diseases and to severe
side effect by drugs. Through a discovery of a large number of SNPs,
we would like to contribute to identification of disease-related
genes and there SNPs in the present database.
Content:The database is derived
from GenBank releases 161, and it contains 494 SNPs of 30 types
of human genetic disorders, along with extensive description of
each genetic disorder, the disease causing gene and there SNPs.
The database contains comprehensive information related to these
genetic disorders such as disease description, their symptoms, diagnosis,
treatment and related gene description; and SNPs description like
SNP name, OMIMID, refseqID, Orientation and strand, allele and its
position, Type of SNP, chromosome number and gene sequence.
Additionally we are planning to include the SNPs information's of
rest genetic disorders of human and other diseases.
